Osteopontin anticorps (C-Term)
Aperçu rapide pour Osteopontin anticorps (C-Term) (ABIN8035141)
Antigène
Voir toutes Osteopontin (SPP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- C-Term
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Fonction
- Anti-Osteopontin/SPP1 Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- different from the related mouse sequence by eight amino acids,and from the related rat sequence by seven amino acids.
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Attributs du produit
- Anti-Osteopontin/SPP1 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminus of human Osteopontin, different from the related mouse sequence by eight amino acids, and from the related rat sequence by seven amino acids.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat, -ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))
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Autre désignation
- SPP1
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Sujet
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Background: Osteopontin (OPN), also known as secreted phosphoprotein 1 (SPP1), is a protein that in humans is encoded by the SPP1 gene (secreted phosphoprotein 1). The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. And the encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. Also, this protein is a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: secreted phosphoprotein 1
Sequence Similarities: Belongs to the osteopontin family.
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Poids moléculaire
- 66 kDa, 25-55 kDa
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ID gène
- 6696
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UniProt
- P10451
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Pathways
- Regulation of Cell Size
Antigène
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