Septin 5 anticorps (C-Term) (Fluoro647)

N° du produit ABIN8035724

Cet anticorps Lapin Polyclonal détecte spécifiquement Septin 5 dans FACS. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour Septin 5 anticorps (C-Term) (Fluoro647) (ABIN8035724)

Antigène: Septin 5 (SEPT5)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Septin 5 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-Septin 5 anticorps (Fluoro647)

Épitope: C-Term

Fonction: Anti-SEPT5/SEPTIN5 Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human SEPT5/SEPTIN5, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Septin 5

Antigène: Septin 5 (SEPT5)

Autre désignation: SEPTIN5

Sujet:

Background: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Gene Full Name: septin 5

ID gène: 5413

UniProt: Q99719

Pathways: Synaptic Vesicle Exocytosis