SH3BP2 anticorps (AA 256-561) (HRP)

N° du produit ABIN8036950

Cet anticorps anti-SH3BP2 Polyclonal Lapin conjugué à HRP (ABIN8036950) détecte spécifiquement SH3BP2 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SH3BP2 anticorps (AA 256-561) (HRP) (ABIN8036950)

Antigène: SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3BP2 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SH3BP2 anticorps (HRP)

Épitope: AA 256-561

Fonction: Anti-3BP2/SH3BP2 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human 3BP2/SH3BP2 recombinant protein (Position: R256-R561).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SH3BP2

Antigène: SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

Autre désignation: SH3BP2

Sujet:

Background: SH3BP2 (SH3 domain-binding protein 2) is a protein that comes from a gene located on Chromosome 4. The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: SH3 domain binding protein 2

ID gène: 6452

UniProt: P78314

Pathways: TCR Signaling