SIGMAR1 anticorps (AA 1-154) (Cy3)

N° du produit ABIN8037288

L’anticorps anti-SIGMAR1 Polyclonal Lapin est utilisé pour la détection de SIGMAR1 dans des échantillons de Humain, Souris, Rat et Singe. Il a été validé pour FACS.

Aperçu rapide pour SIGMAR1 anticorps (AA 1-154) (Cy3) (ABIN8037288)

Antigène: SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIGMAR1 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-SIGMAR1 anticorps (Cy3)

Épitope: AA 1-154

Fonction: Anti-Sigma1-receptor/SIGMAR1 Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Sigma1-receptor/SIGMAR1 recombinant protein (Position: G1-H154).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur SIGMAR1

Antigène: SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

Autre désignation: SIGMAR1

Sujet:

Background: The sigma-1 receptor (σ1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor. In humans, the σ1 receptor is encoded by the SIGMAR1 gene. This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor, it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.

Gene Full Name: sigma non-opioid intracellular receptor 1

ID gène: 10280

UniProt: Q99720

Pathways: SARS-CoV-2 Protein Interactome