SIRT6 anticorps (AA 14-355) (APC)

N° du produit ABIN8037845

Cet anticorps Lapin Polyclonal détecte spécifiquement SIRT6 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SIRT6 anticorps (AA 14-355) (APC) (ABIN8037845)

Antigène: SIRT6 (Sirtuin 6 (SIRT6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT6 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-SIRT6 anticorps (APC)

Épitope: AA 14-355

Fonction: Anti-SIRT6 Antibody APC Conjugated

Homologie: Human SIRT6 shares 82.7% amino acid (aa) sequence identity with both mouse SIRT6.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SIRT6 recombinant protein (Position: D14-S355). Human SIRT6 shares 82.7% amino acid (aa) sequence identity with both mouse SIRT6.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur SIRT6

Antigène: SIRT6 (Sirtuin 6 (SIRT6))

Autre désignation: SIRT6

Sujet:

Background: Sirtuin 6 (SIRT6 or Sirt6) is a stress responsive protein deacetylase and mono-ADP ribosyltransferase enzyme encoded by the SIRT6 gene. This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: sirtuin 6

ID gène: 51548

UniProt: Q8N6T7