SKIL anticorps (AA 1-504) (Fluoro594)

N° du produit ABIN8037919

Cet anticorps anti-SKIL Polyclonal Lapin conjugué à Fluoro594 (ABIN8037919) détecte spécifiquement SKIL dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SKIL anticorps (AA 1-504) (Fluoro594) (ABIN8037919)

Antigène: SKIL (SKI-Like Oncogene (SKIL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKIL est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-SKIL anticorps (Fluoro594)

Épitope: AA 1-504

Fonction: Anti-SnoN/SNO/SKIL Antibody Fluoro594 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SnoN/SNO/SKIL recombinant protein (Position: M1-V504).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur SKIL

Antigène: SKIL (SKI-Like Oncogene (SKIL))

Autre désignation: SKIL

Sujet:

Background: Ski-like protein is a protein that in humans is encoded by the SKIL gene. The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.

Gene Full Name: SKI like proto-oncogene

ID gène: 6498

UniProt: P12757

Pathways: Positive Regulation of Response to DNA Damage Stimulus