SSH1 anticorps (AA 489-921) (HRP)

N° du produit ABIN8037966

L’anticorps anti-SSH1 Polyclonal Lapin est utilisé pour la détection de SSH1 dans des échantillons de Humain. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour SSH1 anticorps (AA 489-921) (HRP) (ABIN8037966)

Antigène: SSH1 (Slingshot Homolog 1 (SSH1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SSH1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SSH1 anticorps (HRP)

Épitope: AA 489-921

Fonction: Anti-SSH1 Antibody HRP Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human SSH1 shares 66.9% amino acid (aa) sequence identity with mouse SSH1.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SSH1 recombinant protein (Position: E489-Y921). Human SSH1 shares 66.9% amino acid (aa) sequence identity with mouse SSH1.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SSH1

Antigène: SSH1 (Slingshot Homolog 1 (SSH1))

Autre désignation: SSH1

Sujet:

Background: Protein phosphatase Slingshot homolog 1 is an enzyme that in humans is encoded by the SSH1 gene. The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: slingshot protein phosphatase 1

ID gène: 54434

UniProt: Q8WYL5

Pathways: CXCR4-mediated Signaling Events