SSH1 anticorps (AA 489-921)

N° du produit ABIN8037970

Cet anticorps anti-SSH1 Polyclonal Lapin (ABIN8037970) détecte spécifiquement SSH1 dans WB, ELISA, FACS, IF et ICC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SSH1 anticorps (AA 489-921) (ABIN8037970)

Antigène: SSH1 (Slingshot Homolog 1 (SSH1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SSH1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Classe de qualité: Carrier-free

Détail du produit anti-SSH1 anticorps

Épitope: AA 489-921

Fonction: Anti-SSH1 Antibody

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human SSH1 shares 66.9% amino acid (aa) sequence identity with mouse SSH1.

Attributs du produit: Anti-SSH1 Antibody. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SSH1 recombinant protein (Position: E489-Y921). Human SSH1 shares 66.9% amino acid (aa) sequence identity with mouse SSH1.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SSH1

Antigène: SSH1 (Slingshot Homolog 1 (SSH1))

Autre désignation: SSH1

Sujet:

Background: Protein phosphatase Slingshot homolog 1 is an enzyme that in humans is encoded by the SSH1 gene. The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: slingshot protein phosphatase 1

Poids moléculaire: 150 kDa

ID gène: 54434

UniProt: Q8WYL5

Pathways: CXCR4-mediated Signaling Events