SLC26A4 anticorps (C-Term) (FITC)

N° du produit ABIN8039996

Cet anticorps Lapin Polyclonal détecte spécifiquement SLC26A4 dans FACS. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour SLC26A4 anticorps (C-Term) (FITC) (ABIN8039996)

Antigène: SLC26A4 (Solute Carrier Family 26, Member 4 (SLC26A4))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC26A4 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-SLC26A4 anticorps (FITC)

Épitope: C-Term

Fonction: Anti-SLC26A4 Antibody FITC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human SLC26A4, which shares 84.4% amino acid (aa) sequence identity with both mouse and rat SCNN1A.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur SLC26A4

Antigène: SLC26A4 (Solute Carrier Family 26, Member 4 (SLC26A4))

Autre désignation: SLC26A4

Sujet:

Background: Pendrin, is an anion exchange protein that in humans is encoded by the SLC26A4 gene. Pendrin is an ion exchanger found in many types of cells in the body. High levels of pendrin expression have been identified in the inner ear and thyroid. In the thyroid, pendrin mediates a component of the efflux of iodide across the apical membrane of the thyrocyte, which is critical for the formation of thyroid hormone. The exact function of pendrin in the inner ear remains unclear, however, pendrin may play a role in acid-base balance as a chloride-bicarbonate exchanger, regulate volume homeostasis through its ability to function as a chloride-formate exchanger or inly modulate the calcium concentration of the endolymph.

Gene Full Name: solute carrier family 26 member 4

ID gène: 5172

UniProt: O43511

Pathways: Thyroid Hormone Synthesis, Sensory Perception of Sound