Spartin (SPART) (AA 205-631) anticorps (FITC)

N° du produit ABIN8041325

Cet anticorps Lapin Polyclonal détecte spécifiquement Spartin dans FACS. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour Spartin (SPART) (AA 205-631) anticorps (FITC) (ABIN8041325)

Antigène: Spartin (SPART)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: FITC

Application: Flow Cytometry (FACS)

Détail du produit

Épitope: AA 205-631

Fonction: Anti-SPART Antibody FITC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SPART recombinant protein (Position: H205-V631).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détail du antigène

Antigène: Spartin (SPART)

Autre désignation: SPART

Sujet:

Background: Spartin is a protein that in humans is encoded by the SPG20 gene. This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).

Gene Full Name: spartin

ID gène: 23111

UniProt: Q8N0X7