Spartin (SPART) (AA 205-631) anticorps
Aperçu rapide pour Spartin (SPART) (AA 205-631) anticorps (ABIN7600578)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 205-631
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Fonction
- Anti-SPART Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-SPART Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human SPART recombinant protein (Position: H205-V631).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- Spartin (SPART)
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Autre désignation
- SPART
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Sujet
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Background: Spartin is a protein that in humans is encoded by the SPG20 gene. This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).
Gene Full Name: spartin
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Poids moléculaire
- 78 kDa
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ID gène
- 23111
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UniProt
- Q8N0X7
Antigène
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