FAM33A anticorps (N-Term) (HRP)

N° du produit ABIN8041758

L’anticorps anti-FAM33A Polyclonal Lapin est utilisé pour la détection de FAM33A dans des échantillons de Humain. Il a été validé pour ELISA, WB et IHC.

Aperçu rapide pour FAM33A anticorps (N-Term) (HRP) (ABIN8041758)

Antigène: FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM33A est conjugé à/à la HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-FAM33A anticorps (HRP)

Épitope: N-Term

Fonction: Anti-SKA2 Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human SKA2, which shares 90.0% amino acid (aa) sequence identity with both mouse and rat SKA2.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur FAM33A

Antigène: FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))

Autre désignation: SKA2

Sujet:

Background: Spindle and kinetochore-associated protein 2 is a protein that in humans is encoded by the SKA2 gene found in chromosome 17.SKA2 is a part of a spindle and kinetochore associated complex also including SKA1 and SKA3 which is responsible for onset of the anaphase in mitosis by regulating chromosomal segregation. SKA2 may function as a prognostic gene marker for identifying lung cancer[3] as well as a proposed biomarker for suicidal tendencies and post-traumatic stress disorders.[4][5] The SKA2 gene contains one single-nucleotide polymorphism (SNP) rs7208505 located in the 3' UTR. This genetic variant containing a cytosine (existing in the less common allele) instead of thymine along with epigenetic modification (such as DNA methylation) is correlated with suicidal tendencies and post-traumatic stress

Gene Full Name: spindle and kinetochore associated complex subunit 2

ID gène: 348235

UniProt: Q8WVK7

Pathways: M Phase