SPON2 anticorps (AA 53-331)

N° du produit ABIN8041983

L’anticorps anti-SPON2 Polyclonal Lapin est utilisé pour la détection de SPON2 dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour SPON2 anticorps (AA 53-331) (ABIN8041983)

Antigène: SPON2 (Spondin 2 (SPON2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPON2 est non-conjugé

Application: Western Blotting (WB), ELISA

Classe de qualité: Carrier-free

Détail du produit anti-SPON2 anticorps

Épitope: AA 53-331

Fonction: Anti-SPON2 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-SPON2 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SPON2 recombinant protein (Position: Q53-V331).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SPON2

Antigène: SPON2 (Spondin 2 (SPON2))

Autre désignation: SPON2

Sujet:

Background: Spondin 2, also known as mindin, is a protein that in humans is encoded by the SPON2 gene. SPON2 (spondin 2, mindin) is an extracellular matrix protein belonging to the mindin/F-spondin family. The protein has two amino terminal follistatin-like (FS) domains and a carboxy terminal thrombospondin type 1 repeat (TSR) domain. The FS domains mediate interactions between SPON2 and integrins, whereas the TSR domain contributes to the role of SPON2 as a pathogen pattern recognition molecule. In that capacity, SPON2 plays an important role in initiation of the innate immune response. It functions as a pattern recognition molecule within the extracellular matrix, where it binds to microbial pathogens and presents them to immune cells. Interactions between SPON2 and integrins are also critical for inflammatory cell recruitment and T cell priming. In addition to its role in innate immunity, SPON2 has also been shown to play a role in hippocampal neuronal outgrowth, cancer metastasis, and diabetic nephropathy.

Gene Full Name: spondin 2

Poids moléculaire: 39 kDa

ID gène: 10417

UniProt: Q9BUD6