TLN1 anticorps (AA 1658-1876)

N° du produit ABIN8045331

L’anticorps anti-TLN1 Monoclonal Souris est utilisé pour la détection de TLN1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et FACS.

Aperçu rapide pour TLN1 anticorps (AA 1658-1876) (ABIN8045331)

Antigène: TLN1 (Talin 1 (TLN1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TLN1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Clone: 2G10D2

Détail du produit anti-TLN1 anticorps

Épitope: AA 1658-1876

Fonction: Anti-Talin 1/TLN1 Antibody (monoclonal, 2G10D2)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Talin 1/TLN1 Antibody.(monoclonal, 2G10D2). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Talin 1/TLN1 recombinant protein (Position: Q1658-N1876).

Isotype: IgG1

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TLN1

Antigène: TLN1 (Talin 1 (TLN1))

Autre désignation: TLN1

Sujet:

Background: Talin-1 is a protein that in humans is encoded by the TLN1 gene. This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.

Gene Full Name: talin 1

Poids moléculaire: 250-270 kDa

ID gène: 7094

UniProt: Q9Y490

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location