TBP anticorps (Middle Region)
Aperçu rapide pour TBP anticorps (Middle Region) (ABIN8045507)
Antigène
Voir toutes TBP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- Middle Region
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Fonction
- Anti-TATA binding protein TBP Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- identical to the related rat,mouse sequences.
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Attributs du produit
- Anti-TATA binding protein TBP Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- A synthetic peptide corresponding to a sequence in the middle region of human TBP, identical to the related rat and mouse sequences.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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Agent conservateur
- Sodium azide, Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- TBP (TATA Box Binding Protein (TBP))
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Autre désignation
- TBP
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Sujet
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Background: TBP, TATA-binding protein, is a general transcription factor that binds specifically to a DNA sequence called the TATA box. The TBP gene is mapped to 6q27. This DNA sequence is found about 35 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP, along with a variety of TBP-associated factors, make up the TFIID, a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitiation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20 % of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II.
Gene Full Name: TATA-box binding protein
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Poids moléculaire
- 31 kDa
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ID gène
- 6908
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UniProt
- P20226
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Pathways
- Signalisation WNT
Antigène
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