TGIF1 anticorps (AA 26-401) (Fluoro647)

N° du produit ABIN8046091

Cet anticorps anti-TGIF1 Polyclonal Lapin conjugué à Fluoro647 (ABIN8046091) détecte spécifiquement TGIF1 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TGIF1 anticorps (AA 26-401) (Fluoro647) (ABIN8046091)

Antigène: TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TGIF1 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-TGIF1 anticorps (Fluoro647)

Épitope: AA 26-401

Fonction: Anti-TGIF/TGIF1 Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TGIF/TGIF1 recombinant protein (Position: D26-A401).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur TGIF1

Antigène: TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

Autre désignation: TGIF1

Sujet:

Background: Homeobox protein TGIF1 is a protein that, in humans, is encoded by the TGIF1 gene. The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described.

Gene Full Name: TGFB induced factor homeobox 1

ID gène: 7050

UniProt: Q15583

Pathways: Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation