TREX1 anticorps (Middle Region) (HRP)

N° du produit ABIN8046297

L’anticorps anti-TREX1 Polyclonal Lapin est utilisé pour la détection de TREX1 dans des échantillons de Humain. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour TREX1 anticorps (Middle Region) (HRP) (ABIN8046297)

Antigène: TREX1 (three Prime Repair Exonuclease 1 (TREX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TREX1 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-TREX1 anticorps (HRP)

Épitope: Middle Region

Fonction: Anti-TREX1 Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse sequence by four amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human TREX1, different from the related mouse sequence by four amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TREX1

Antigène: TREX1 (three Prime Repair Exonuclease 1 (TREX1))

Autre désignation: TREX1

Sujet:

Background: Three prime repair exonuclease 1 is an enzyme that in humans is encoded by the TREX1 gene. This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants.

Gene Full Name: three prime repair exonuclease 1

ID gène: 11277

UniProt: Q9NSU2

Pathways: Apoptose