Thrombopoietin anticorps (AA 22-259) (Fluoro488)

N° du produit ABIN8046348

L’anticorps anti-Thrombopoietin Polyclonal Lapin est utilisé pour la détection de Thrombopoietin dans des échantillons de Rat et Souris. Il a été validé pour FACS.

Aperçu rapide pour Thrombopoietin anticorps (AA 22-259) (Fluoro488) (ABIN8046348)

Antigène: Thrombopoietin (THPO)

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Thrombopoietin est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-Thrombopoietin anticorps (Fluoro488)

Épitope: AA 22-259

Fonction: Anti-Thrombopoietin/Thpo Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: coli-derived mouse Thrombopoietin recombinant protein (Position: S22-H259). Mouse Thrombopoietin shares 79.3%,92.9% amino acid (aa) sequence identity with human,rat Thrombopoietin,respectively.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived mouse Thrombopoietin recombinant protein (Position: S22-H259). Mouse Thrombopoietin shares 79.3% and 92.9% amino acid (aa) sequence identity with human and rat Thrombopoietin, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Thrombopoietin

Antigène: Thrombopoietin (THPO)

Autre désignation: Thpo

Sujet:

Background: Thrombopoietin (THPO), also known as megakaryocyte growth and development factor (MGDF), is a protein that in humans is encoded by the THPO gene. Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.

Gene Full Name: thrombopoietin

ID gène: 21832

UniProt: P40226

Pathways: Signalistation JAK/STAT, Hormone Activity