Thrombopoietin anticorps (N-Term)

N° du produit ABIN8046378

L’anticorps anti-Thrombopoietin Polyclonal Lapin est utilisé pour la détection de Thrombopoietin dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB.

Aperçu rapide pour Thrombopoietin anticorps (N-Term) (ABIN8046378)

Antigène: Thrombopoietin (THPO)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Thrombopoietin est non-conjugé

Application: Western Blotting (WB)

Classe de qualité: Carrier-free

Détail du produit anti-Thrombopoietin anticorps

Épitope: N-Term

Fonction: Anti-Thrombopoietin/THPO Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Thrombopoietin/THPO Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Thrombopoietin/THPO, which shares 89.2% amino acid (aa) sequence identity with both mouse and rat Thrombopoietin/THPO.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Thrombopoietin

Antigène: Thrombopoietin (THPO)

Autre désignation: THPO

Sujet:

Background: Thrombopoietin (THPO), also known as megakaryocyte growth and development factor (MGDF), is a protein that in humans is encoded by the THPO gene. Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.

Gene Full Name: thrombopoietin

Poids moléculaire: 38 kDa

ID gène: 7066

UniProt: P40225

Pathways: Signalistation JAK/STAT, Hormone Activity