TJP3 anticorps (C-Term) (HRP)

N° du produit ABIN8046803

Cet anticorps Lapin Polyclonal détecte spécifiquement TJP3 dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour TJP3 anticorps (C-Term) (HRP) (ABIN8046803)

Antigène: TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TJP3 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-TJP3 anticorps (HRP)

Épitope: C-Term

Fonction: Anti-Zonula occludens protein 3/TJP3 Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related rat sequence.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Zonula occludens protein 3, identical to the related rat sequence.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TJP3

Antigène: TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))

Autre désignation: TJP3

Sujet:

Background: TJP3 (TIGHT JUNCTION PROTEIN 3), also called ZO3, is a protein that in humans is encoded by the TJP3 gene. TJP3 is a member of the family of membrane-associated guanylate kinase-like proteins (MAGUK) that associate with intracellular junctions (Itoh et al., 1999). Haskins et al. (1998) showed that recombinant Tjp3 binds in vitro translated Tjp1 and binds ly to the cytoplasmic tail of occludin but no binding was detected between Tjp3 and Tjp2. Roh et al. (2002) determined that Tjp3 interacted with PATJ (INADL) and that both proteins colocalized to tight junctions in vivo. In vitro studies showed that the sixth and eighth PDZ domains of PATJ mediated interaction with the Tjp3 C-terminal domain and with Cldn1, respectively.

Gene Full Name: tight junction protein 3

Sequence Similarities: Belongs to the MAGUK family.

ID gène: 27375

UniProt: Q9QXY1