TOLLIP anticorps (C-Term) (FITC)

N° du produit ABIN8047253

Cet anticorps Lapin Polyclonal détecte spécifiquement TOLLIP dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TOLLIP anticorps (C-Term) (FITC) (ABIN8047253)

Antigène: TOLLIP (Toll Interacting Protein (TOLLIP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOLLIP est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-TOLLIP anticorps (FITC)

Épitope: C-Term

Fonction: Anti-Toll-interacting protein Tollip Antibody FITC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Tollip.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur TOLLIP

Antigène: TOLLIP (Toll Interacting Protein (TOLLIP))

Autre désignation: TOLLIP

Sujet:

Background: TOLLIP (TOLL-Interacting Protein), is an inhibitory adaptor protein that in humans is encoded by the TOLLIP gene. Lo et al. (2009) stated that the TOLLIP gene maps to chromosome 11. The mouse gene maps to chromosome 7. By Western blot analysis of embryonic kidney cells, Burns et al. (2000) confirmed the binding of TOLLIP to IL1RAP, to a complex of IL1RAP-IL1R1, and to IL18R. Burns et al. (2000) proposed that IL1B stimulation induces aggregation of IL1Rs, recruitment of MYD88 followed by TOLLIP-IRAK complexes, and the phosphorylation of IRAK by MYD88. This leads to the dissociation of TOLLIP from IRAK, which can then transmit the IL1-induced signals.

Gene Full Name: toll interacting protein

Sequence Similarities: Belongs to the tollip family.

ID gène: 54472

UniProt: Q9H0E2