TLR8 anticorps (C-Term) (Biotin)

N° du produit ABIN8047468

Cet anticorps anti-TLR8 Polyclonal Lapin conjugué à Biotin (ABIN8047468) détecte spécifiquement TLR8 dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Rat.

Aperçu rapide pour TLR8 anticorps (C-Term) (Biotin) (ABIN8047468)

Antigène: TLR8 (Toll-Like Receptor 8 (TLR8))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR8 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-TLR8 anticorps (Biotin)

Épitope: C-Term

Fonction: Anti-Toll-like receptor 8 TLR8 Antibody Biotin Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse sequence by one amino acid.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of rat TLR8, different from the related mouse sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TLR8

Antigène: TLR8 (Toll-Like Receptor 8 (TLR8))

Autre désignation: TLR8

Sujet:

Background: TLR8 (Toll-like receptor 8) is a protein that in humans is encoded by the TLR8 gene. TLR8 has also been designated as CD288 (cluster of differentiation 288). The TLR8 gene is mapped to Xp22.3-p22.2 by Chuang and Ulevitch (2000) and Du et al. (2000). The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. TLR8 recognises G-rich oligonucleotides.

Gene Full Name: toll-like receptor 8

Sequence Similarities: Belongs to the Toll-like receptor family.

ID gène: 684440

UniProt: A5H300

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades