TLR8 anticorps (C-Term)

N° du produit ABIN8047478

Cet anticorps Lapin Polyclonal détecte spécifiquement TLR8 dans WB. Il présente une réactivité avec des échantillons de Rat.

Aperçu rapide pour TLR8 anticorps (C-Term) (ABIN8047478)

Antigène: TLR8 (Toll-Like Receptor 8 (TLR8))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR8 est non-conjugé

Application: Western Blotting (WB)

Classe de qualité: Carrier-free

Détail du produit anti-TLR8 anticorps

Épitope: C-Term

Fonction: Anti-Toll-like receptor 8 TLR8 Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse sequence by one amino acid.

Attributs du produit: Anti-Toll-like receptor 8 TLR8 Antibody. Tested in WB applications. This antibody reacts with Rat.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of rat TLR8, different from the related mouse sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Rat

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur TLR8

Antigène: TLR8 (Toll-Like Receptor 8 (TLR8))

Autre désignation: TLR8

Sujet:

Background: TLR8 (Toll-like receptor 8) is a protein that in humans is encoded by the TLR8 gene. TLR8 has also been designated as CD288 (cluster of differentiation 288). The TLR8 gene is mapped to Xp22.3-p22.2 by Chuang and Ulevitch (2000) and Du et al. (2000). The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. TLR8 recognises G-rich oligonucleotides.

Gene Full Name: toll-like receptor 8

Sequence Similarities: Belongs to the Toll-like receptor family.

Poids moléculaire: 150 kDa

ID gène: 684440

UniProt: A5H300

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades