TRIB2 anticorps (Middle Region) (Fluoro550)

N° du produit ABIN8049475

Cet anticorps anti-TRIB2 Polyclonal Lapin conjugué à Fluoro550 (ABIN8049475) détecte spécifiquement TRIB2 dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TRIB2 anticorps (Middle Region) (Fluoro550) (ABIN8049475)

Antigène: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIB2 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-TRIB2 anticorps (Fluoro550)

Épitope: Middle Region

Fonction: Anti-TRIB2 Antibody Fluoro550 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse sequence.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human TRIB2, identical to the related mouse sequence.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur TRIB2

Antigène: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Autre désignation: TRIB2

Sujet:

Background: Tribbles homolog 2 is a protein that in humans is encoded by the TRIB2 gene. This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBP alpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.

Gene Full Name: tribbles pseudokinase 2

ID gène: 28951

UniProt: Q92519