F12 anticorps

N° du produit ABIN8065427

Cet anticorps Souris Monoclonal détecte spécifiquement F12 dans ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour F12 anticorps (ABIN8065427)

Antigène: F12 (Coagulation Factor XII (F12))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp F12 est non-conjugé

Application: ELISA

Classe de qualité: Carrier-free

Clone: 10-11-05

Détail du produit anti-F12 anticorps

Fonction: Anti-Factor XII (heavy chain) Antibody

Specificité: CAM 011-05 binds the heavy chain of human factor XII, including factor XII derivatives such as α-factor XIIa and α-factor XIIa C1-inhibitor complexes. Differs from CAM 011-37.

Homologie: Human

Purification: Protein A or Protein G purified

Immunogène: Affinity purified human factor XII.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2-8°C without exposure to light

Date de péremption: 12 months

Détails sur F12

Antigène: F12 (Coagulation Factor XII (F12))

Autre désignation: Factor XII

Sujet: F12, HAE3, HAEX, HAF, coagulation factor XII, Hageman factor, Plasma coagulation Factor XIIa, beta-factor XIIa part 1, beta-factor XIIa part 2, coagulation factor XIIa heavy chain, coagulation factor XIIa light chain,Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (PubMed:2019570, PubMed:21304106, PubMed:8427954). {ECO:0000269|PubMed:2019570, ECO:0000269|PubMed:21304106, ECO:0000269|PubMed:8427954}.,F12,Factor XII is a component in the coagulation cascade. It is a plasma glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII to a-factor XIIa, which in turn activates factor XI to factor XIa.

Poids moléculaire: 50 kDa

ID gène: 2161

UniProt: P00748

Pathways: Système du Complément