CDC25B anticorps (pSer353) (Cy3)

N° du produit ABIN756985

Cet anticorps Lapin Polyclonal détecte spécifiquement CDC25B dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour CDC25B anticorps (pSer353) (Cy3) (ABIN756985)

Antigène: CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC25B est conjugé à/à la Cy3

Application: Western Blotting (WB)

Détail du produit anti-CDC25B anticorps (Cy3)

Épitope: pSer353

Specificité: This phosphorylation site is homologous to that of Ser351 in Mouse and Ser 349 in Rat.

Réactivité croisée: Humain, Souris

Homologie: Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Cdc25B around the phosphorylation site of Ser353

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CDC25B

Antigène: CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))

Autre désignation: Cdc25b

Sujet:

Synonyms: M-phase inducer phosphatase 2, Dual specificity phosphatase Cdc25B, CDC25B, CDC25HU2

Background: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.

ID gène: 994

UniProt: P30305

Pathways: Cycle Cellulaire, M Phase, Autophagy