DOK1 anticorps (pTyr362)
Aperçu rapide pour DOK1 anticorps (pTyr362) (ABIN757642)
Antigène
Voir toutes DOK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pTyr362
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Réactivité croisée
- Humain
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Homologie
- Mouse,Rat,Dog,Cow,Pig
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic phosphopeptide derived from human DOK1 around the phosphorylation site of Tyr362
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
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Autre désignation
- DOK1
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Sujet
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Synonyms: DOK1 phospho Y362, DOK1 phospho Tyr362, p-DOK1 phospho Y362, docking protein 1 downstream of tyrosine kinase 1, Docking protein 1 p62dok Downstream of tyrosine kinase 1 pp62., docking protein 1 62kD downstream of tyrosine kinase 1, Docking protein 1 62kD, Docking protein 1 62kD, Docking protein 1, DOK 1, DOK1, DOK-1, DOK1_HUMAN, Downstream of tyrosine kinase 1, p62dok, P62DOK, pp62, pp62.
Background: Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
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ID gène
- 1796
Antigène
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