DOK1 anticorps (pTyr398)

N° du produit ABIN6256732

Détail du produit anti-DOK1 anticorps

Antigène: DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))

Épitope: pTyr398

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Phospho-p62 Dok (Tyr398) Antibody detects endogenous levels of p62 Dok only when phosphorylated at Tyrosine 398.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogène: A synthesized peptide derived from human p62 Dok around the phosphorylation site of Tyr398.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur DOK1

Antigène: DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))

Autre désignation: DOK1 (DOK1 Produits)

Synonymes: anticorps P62DOK, anticorps Dok-1, anticorps AW557123, anticorps p62DOK, anticorps dok1, anticorps zgc:76914, anticorps docking protein 1, anticorps docking protein 1b, anticorps DOK1, anticorps Dok1, anticorps dok1b

Sujet:

Description: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

Gene: DOK1

Poids moléculaire: 62kDa

ID gène: 1796

UniProt: Q99704