Recombinant CEACAM6 anticorps

N° du produit ABIN8093035

Cet anticorps Lapin Monoclonal détecte spécifiquement CEACAM6 dans WB, IHC et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant CEACAM6 anticorps (ABIN8093035)

Antigène: CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CEACAM6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Clone: CEACAM6-13371R

Détail du produit anti-CEACAM6 anticorps

Fonction: CEACAM6 Antibody / Carcinoembryonic antigen-related cell adhesion molecule 6 (azide and preservative free)

Immunogène: Recombinant CEACAM6 protein was used as the immunogen for the CEACAM6/Carcinoembryonic antigen-related cell adhesion molecule 6 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: 1. Optimal dilution of the CEACAM6/Carcinoembryonic antigen-related cell adhesion molecule 6 antibody should be determined by the researcher.

2. This CEACAM6/Carcinoembryonic antigen-related cell adhesion molecule 6 antibody is recombinantly produced by expression in CHO cells.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: CEACAM6/Carcinoembryonic antigen-related cell adhesion molecule 6 antibody with sodium azide - store at 2 to 8oC, antibody without sodium azide - store at -20 to -80oC.

Détails sur CEACAM6

Antigène: CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))

Autre désignation: CEACAM6

Sujet: CEACAM6 antibody (clone CEACAM6/13371R) targets Carcinoembryonic Antigen Related Cell Adhesion Molecule 6, a glycosylphosphatidylinositol-anchored cell surface glycoprotein encoded by the human CEACAM6 gene. CEACAM6, also widely referred to as CD66c in immunology literature, is a member of the carcinoembryonic antigen related cell adhesion molecule family involved in intercellular adhesion and immune regulation. CEACAM6 antibody is commonly used in studies of epithelial biology, tumor progression, and inflammatory signaling because CEACAM6 expression is frequently elevated in multiple carcinomas.

CEACAM6 is localized to the plasma membrane via a GPI anchor and mediates homophilic and heterophilic cell-cell interactions. In normal tissues, CEACAM6 is expressed on granulocytes and certain epithelial cells, including those of the gastrointestinal and respiratory tracts. Overexpression of CEACAM6 has been reported in colorectal, pancreatic, gastric, breast, and lung cancers, where it has been associated with tumor cell adhesion, invasion, and resistance to apoptosis. CEACAM6 antibody clone CEACAM6/13371R supports detection of CEACAM6 expression in epithelial tumors and immune cell populations in research applications.

Functionally, CEACAM6 participates in signaling pathways that influence cell survival, proliferation, and metastatic potential. Increased CEACAM6 expression has been linked to enhanced tumor cell motility and reduced anoikis sensitivity, contributing to cancer progression. Because of its cell surface localization and tumor-associated overexpression, CEACAM6 antibody is frequently applied in cancer biology and translational oncology research.

Structurally, CEACAM6 contains immunoglobulin-like extracellular domains characteristic of the CEACAM family and lacks a transmembrane domain due to its GPI anchorage. A CEACAM6 antibody such as clone CEACAM6/13371R is suitable for detecting CEACAM6 expression in epithelial tissues and tumor specimens in research settings.

UniProt: P40199