Isocitrate Dehydrogenase anticorps

N° du produit ABIN8093273

L’anticorps anti-Isocitrate Dehydrogenase Monoclonal Souris est utilisé pour la détection de Isocitrate Dehydrogenase dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, IF, IHC (p) et FACS.

Aperçu rapide pour Isocitrate Dehydrogenase anticorps (ABIN8093273)

Antigène: Isocitrate Dehydrogenase (IDH)

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Isocitrate Dehydrogenase est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 6B13

Détail du produit anti-Isocitrate Dehydrogenase anticorps

Fonction: Isocitrate Dehydrogenase 2 / IDH2

Séquence: KDLAGCIHGL SNVKLNEHFL NTTDFLDTIK SNLDR

Purification: Affinity purified

Immunogène: Amino acids KDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDR from the human protein were used as the immunogen for the Isocitrate Dehydrogenase 2 antibody.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal dilution of the Isocitrate Dehydrogenase 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Isocitrate Dehydrogenase 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Isocitrate Dehydrogenase

Antigène: Isocitrate Dehydrogenase (IDH)

Autre désignation: Isocitrate Dehydrogenase 2 / IDH2

Sujet: Isocitrate dehydrogenase [NADP], mitochondrial is an enzyme that in humans is encoded by the IDH2 gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.

UniProt: P48735