IL13 Receptor alpha 1 anticorps (N-Term)

N° du produit ABIN8103334

Cet anticorps Lapin Polyclonal détecte spécifiquement IL13 Receptor alpha 1 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Lapin, Boeuf (Vache), Cobaye, Cheval, Porc, Mouton et Chien.

Aperçu rapide pour IL13 Receptor alpha 1 anticorps (N-Term) (ABIN8103334)

Antigène: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Cobaye, Cheval, Porc, Mouton, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL13 Receptor alpha 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IL13 Receptor alpha 1 anticorps

Épitope: N-Term

Fonction: IL13RA1 Antibody - N-terminal region

Séquence: YFSHFGDKQD KKIAPETRRS IEVPLNERIC LQVGSQCSTN ESEKPSILVE

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human I13R1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63415-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur IL13 Receptor alpha 1

Antigène: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Autre désignation: IL13RA1

Sujet:

Background Information: The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

Gene Name: interleukin 13 receptor subunit alpha 1

Alternative Symbols: NR4, CT19, CD213A1, IL-13Ra

Protein Name: interleukin-13 receptor subunit alpha-1

Poids moléculaire: 46kDa

ID gène: 3597

NCBI Accession: NP_001551

UniProt: P78552

Pathways: Signalistation JAK/STAT, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response