AIMP1 anticorps (AA 201-300) (HRP)

N° du produit ABIN759665

L’anticorps Lapin Polyclonal anti-AIMP1 a été validé pour WB, ELISA, IHC (p) et IHC (fro). Il convient pour détecter AIMP1 dans des échantillons de Humain.

Aperçu rapide pour AIMP1 anticorps (AA 201-300) (HRP) (ABIN759665)

Antigène: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AIMP1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-AIMP1 anticorps (HRP)

Épitope: AA 201-300

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EMAP2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur AIMP1

Antigène: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Autre désignation: EMAP2

Sujet:

Synonyms: AIMP 1, Aimp1, AIMP1/p43, AIMP1_HUMAN , Aminoacyl tRNA synthetase complex-interacting multunctional protein 1, ARS interacting multunctional protein 1, ARS-interacting multunctional protein 1, EMAP 2, EMAP-2, EMAP-II, EMAP II, EMAP2, EMAPII, Endothelial monocyte activating polypeptide 2, Endothelial Monocyte Activating Polypeptide, Endothelial monocyte-activating polypeptide 2, Endothelial monocyte-activating polypeptide II, Multisynthase complex auxiliary component p43, Multisynthetase complex auxiliary component p43, p43 antibody Scye 1, Scye1, Small Inducible Cytokine Subfamily E Member 1, Small inducible cytokine subfamily E, member 1 endothelial monocyte-activating.

Background: Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.

ID gène: 9255