LIN28B anticorps (C-Term)

N° du produit ABIN8104468

Cet anticorps Lapin Polyclonal détecte spécifiquement LIN28B dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Mouton, Chien, Cobaye et Lapin.

Aperçu rapide pour LIN28B anticorps (C-Term) (ABIN8104468)

Antigène: LIN28B (Lin-28 Homolog B (LIN28B))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Mouton, Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIN28B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LIN28B anticorps

Épitope: C-Term

Fonction: LIN28B Antibody - C-terminal region

Séquence: GCTSPPFPQE ARAEISERSG RSPQEASSTK SSIAPEEQSK KGPSVQKRKK

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 86%, Rat: 93%, Sheep: 100%

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human LN28B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50332-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur LIN28B

Antigène: LIN28B (Lin-28 Homolog B (LIN28B))

Autre désignation: LIN28B

Sujet:

Background Information: The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation.

Gene Name: lin-28 homolog B

Alternative Symbols: CSDD2

Protein Name: protein lin-28 homolog B

Poids moléculaire: 27kDa

ID gène: 389421

NCBI Accession: NP_001004317

UniProt: Q6ZN17