PRDM12 anticorps (C-Term)

N° du produit ABIN8108788

Cet anticorps Lapin Polyclonal détecte spécifiquement PRDM12 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cobaye et Lapin.

Aperçu rapide pour PRDM12 anticorps (C-Term) (ABIN8108788)

Antigène: PRDM12 (PR Domain Containing 12 (PRDM12))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRDM12 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PRDM12 anticorps

Épitope: C-Term

Fonction: PRDM12 Antibody - C-terminal region

Séquence: IPGVPGLEED QKKNKHEDFH PADSAAGPAG RMRCVICHRG FNSRSNLRSH

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PRD12

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33217-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PRDM12

Antigène: PRDM12 (PR Domain Containing 12 (PRDM12))

Autre désignation: PRDM12

Sujet:

Background Information: This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia.

Gene Name: PR/SET domain 12

Alternative Symbols: PFM9, HSAN8

Protein Name: PR domain zinc finger protein 12

Poids moléculaire: 40kDa

ID gène: 59335

NCBI Accession: NP_067632

UniProt: Q9H4Q4