POT1 anticorps (C-Term)

N° du produit ABIN8109220

Cet anticorps Lapin Polyclonal détecte spécifiquement POT1 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour POT1 anticorps (C-Term) (ABIN8109220)

Antigène: POT1 (Protection of Telomeres 1 (POT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POT1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-POT1 anticorps

Épitope: C-Term

Fonction: POT1 Antibody - C-terminal region

Séquence: QNTSLYDSKI WTTKNQKGRK VAVHFVKNNG ILPLSNECLL LIEGGTLSEI

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human POTE1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74137-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur POT1

Antigène: POT1 (Protection of Telomeres 1 (POT1))

Autre désignation: POT1

Sujet:

Background Information: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

Gene Name: protection of telomeres 1

Alternative Symbols: GLM9, CMM10, HPOT1

Protein Name: protection of telomeres protein 1

Poids moléculaire: 69kDa

ID gène: 25913

NCBI Accession: XP_006715980

UniProt: Q9NUX5

Pathways: Cycle Cellulaire, Telomere Maintenance