Thyroperoxidase anticorps (C-Term)

N° du produit ABIN8114021

L’anticorps anti-Thyroperoxidase Polyclonal Lapin est utilisé pour la détection de Thyroperoxidase dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour Thyroperoxidase anticorps (C-Term) (ABIN8114021)

Antigène: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Thyroperoxidase est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Thyroperoxidase anticorps

Épitope: C-Term

Fonction: TPO Antibody - C-terminal region

Séquence: VQDQLMNEEL TERLFVLSNS STLDLASINL QRGRDHGLPG YNEWREFCGL

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TPO

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44312-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Thyroperoxidase

Antigène: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Autre désignation: TPO

Sujet:

Background Information: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.

Gene Name: thyroid peroxidase

Alternative Symbols: MSA, TPX, TDH2A

Protein Name: Thyroid peroxidase

Poids moléculaire: 83 kDa

ID gène: 7173

NCBI Accession: NP_000538

UniProt: P07202

Pathways: Thyroid Hormone Synthesis