BBS7 anticorps (AA 85-135)

N° du produit ABIN8119957

Cet anticorps anti-BBS7 Polyclonal Lapin (ABIN8119957) détecte spécifiquement BBS7 dans WB. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour BBS7 anticorps (AA 85-135) (ABIN8119957)

Antigène: BBS7 (Bardet-Biedl Syndrome 7 (BBS7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BBS7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BBS7 anticorps

Épitope: AA 85-135

Fonction: BBS7 Antibody

Specificité: This antibody detects endogenous levels of BBS7 at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human BBS7 AA range: 85-135

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur BBS7

Antigène: BBS7 (Bardet-Biedl Syndrome 7 (BBS7))

Autre désignation: BBS7

Sujet:

Background: This gene encodes one of eight proteins that form the BBSome complex containing BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSome complex assembly is mediated by a complex composed of three chaperonin-like BBS proteins (BBS6, BBS10, and BBS12) and CCT/TRiC family chaperonins. Mutations in this gene are implicated in Bardet-Biedl syndrome, a genetic disorder whose symptoms include obesity, retinal degeneration, polydactyly and nephropathy, however, mutations in this gene and the BBS8 gene are thought to play a minor role and mutations in chaperonin-like BBS genes are found to be a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. Two transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq, Oct 2014],

Gene Name: BBS7 BBS2L1

Protein Name: BBS7

ID gène: 55212

UniProt: Q8IWZ6

Pathways: Signalisation Hedgehog