BIK anticorps (pSer35)

N° du produit ABIN8119970

Cet anticorps Lapin Polyclonal détecte spécifiquement BIK dans IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BIK anticorps (pSer35) (ABIN8119970)

Antigène: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIK est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-BIK anticorps

Épitope: pSer35

Fonction: NBK (phospho Ser35) Antibody

Specificité: Phospho-NBK (S35) Polyclonal Antibody detects endogenous levels of NBK protein only when phosphorylated at S35.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized phospho-peptide around the phosphorylation site of human NBK (phospho Ser35)

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur BIK

Antigène: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Autre désignation: NBK

Sujet:

Synonyms: BIK, NBK, Bcl-2-interacting killer, Apoptosis inducer NBK, BIP1, BP4

Background: The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011],

Gene Name: BIK

Protein Name: Bcl-2-interacting killer

ID gène: 638

UniProt: Q13323

Pathways: Positive Regulation of Endopeptidase Activity