BACE1 anticorps (pSer498)
Aperçu rapide pour BACE1 anticorps (pSer498) (ABIN8119990)
Antigène
Voir toutes BACE1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer498
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Fonction
- BACE (Phospho Ser498) Antibody
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Specificité
- This antibody detects endogenous levels of Human,Mouse,Rat BACE (Phospho Ser498)
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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Immunogène
- Synthesized peptide derived from human BACE (Phospho Ser498)
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Isotype
- IgG
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Indications d'application
- WB 1:1000-2000 ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- BACE1 (Beta-secretase 1 (BACE1))
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Autre désignation
- BACE
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Sujet
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Synonyms: Beta-secretase 1 (EC 3.4.23.46; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2)
Background: beta-secretase 1(BACE1) Homo sapiens This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015],
Gene Name: BACE1 BACE KIAA1149
Protein Name: BACE (Phospho Ser498)
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ID gène
- 23621
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UniProt
- P56817
Antigène
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