BMI1 anticorps

N° du produit ABIN8120003

Cet anticorps Lapin Polyclonal détecte spécifiquement BMI1 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour BMI1 anticorps (ABIN8120003)

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMI1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BMI1 anticorps

Fonction: Bmi-1 Antibody(F270)

Specificité: This antibody detects endogenous levels of human Bmi-1

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Recombinant Protein derived from human Bmi-1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur BMI1

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Autre désignation: Bmi-1

Sujet:

Synonyms: Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)

Background: BMI1 proto-oncogene, polycomb ring finger(BMI1) Homo sapiens This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015],

Gene Name: BMI1 PCGF4 RNF51

Protein Name: Bmi-1

ID gène: 100532731

UniProt: P35226

Pathways: Cycle Cellulaire, Autophagy