Cadherin 4 anticorps (AA 150-250)

N° du produit ABIN8120093

Cet anticorps Souris Monoclonal détecte spécifiquement Cadherin 4 dans WB, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Cadherin 4 anticorps (AA 150-250) (ABIN8120093)

Antigène: Cadherin 4 (CDH4)

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cadherin 4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: AB2351

Détail du produit anti-Cadherin 4 anticorps

Épitope: AA 150-250

Fonction: R-Cadherin mouse mAb

Specificité: This antibody detects endogenous levels of R-Cadherin protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 150 - 250 of the human R - Cadherin protein.

Isotype: IgG

Information d'application

Indications d'application: WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur Cadherin 4

Antigène: Cadherin 4 (CDH4)

Autre désignation: R-Cadherin

Sujet:

Synonyms: Cadherin-4, Retinal cadherin, R-CAD, R-cadherin

Background: cadherin 4 (CDH4) Homo sapiens This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],

Gene Name: CDH4

Protein Name: R-Cadherin

ID gène: 1002

UniProt: P55283

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size