Cathepsin D anticorps
Aperçu rapide pour Cathepsin D anticorps (ABIN8120276)
Antigène
Voir toutes Cathepsin D (CTSD) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Cathepsin D Rabbit mAb
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Specificité
- This antibody detects endogenous levels of Cathepsin D protein.
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Purification
- The antibody was purified by protein A affinity chromatography.
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Immunogène
- Recombinant protein (or fragment).
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Isotype
- IgG
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Indications d'application
- WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at-20°C. Avoid freeze / thaw cycles.
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- Cathepsin D (CTSD)
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Autre désignation
- Cathepsin D
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Sujet
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Synonyms: CTSD, CPSD, Cathepsin D
Background: This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer&apos, s disease. [provided by RefSeq, Nov 2015],
Gene Name: CTSD
Protein Name: Cathepsin D
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ID gène
- 1509
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UniProt
- P07339
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Pathways
- Peptide Hormone Metabolism
Antigène
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