Claudin 7 anticorps (AA 100-211)

N° du produit ABIN8120612

Cet anticorps Souris Monoclonal détecte spécifiquement Claudin 7 dans IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Claudin 7 anticorps (AA 100-211) (ABIN8120612)

Antigène: Claudin 7 (CLDN7)

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Claudin 7 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: AB1433

Détail du produit anti-Claudin 7 anticorps

Épitope: AA 100-211

Fonction: Claudin 7 Mouse mAb (Ready to Use)

Specificité: The antibody can specifically recognize human Claudin 7 protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 100 - 211 of the human Claudin 7 protein.

Isotype: IgG

Information d'application

Indications d'application: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze

Stock: 4 °C

Stockage commentaire: Store at 4°C. Avoid freeze.

Détails sur Claudin 7

Antigène: Claudin 7 (CLDN7)

Autre désignation: Claudin 7

Sujet:

Synonyms: CEPTR L2, CEPTRL 2, CEPTRL2, Claudin 1, Claudin 7, Claudin 9, Claudin-7, Claudin1, Claudin7, Claudin9, CLD7_HUMAN, CLDN 7, CLDN-7, CLDN7, Clostridium perfringens enterotoxin receptor like 2, CPETR L2, CPETRL 2, CPETRL2, Hs. 84359

Background: Claudin 7 is a 22 kDa membrane protein, belonging to the tight junction protein family. Claudin family proteins play an important role in cell polarity, signal transduction and the pathogenesis of a variety of malignant tumors. It has been reported that compared with non neoplastic mucosal tissues, the expression of claudin 7 in laryngeal squamous cell carcinoma is down- regulated, and the expression level is related to distant metastasis, which can be used as a potential predictor of poor prognosis. Therefore, claudin 7 may be a useful immunohistochemical marker for the diagnosis, metastasis and prognosis of laryngeal cancer.

Gene Name: CLDN7 CEPTRL2 CPETRL2

Protein Name: Claudin 7

ID gène: 1366

UniProt: O95471

Pathways: Hepatitis C