Claudin 7 anticorps (AA 100-211)

N° du produit ABIN8120614

Cet anticorps anti-Claudin 7 Monoclonal Souris (Clone AB1433) (ABIN8120614) détecte spécifiquement Claudin 7 dans IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Claudin 7 anticorps (AA 100-211) (ABIN8120614)

Antigène: Claudin 7 (CLDN7)

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Claudin 7 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: AB1433

Détail du produit anti-Claudin 7 anticorps

Épitope: AA 100-211

Fonction: Claudin 7 mouse mAb

Specificité: The antibody can specifically recognize human Claudin 7 protein.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogène: A synthetic peptide corresponding to the amino acid region 100 - 211 of the human Claudin 7 protein.

Isotype: IgG

Information d'application

Indications d'application: IHC, 1:200-1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur Claudin 7

Antigène: Claudin 7 (CLDN7)

Autre désignation: Claudin 7

Sujet:

Synonyms: CEPTR L2, CEPTRL 2, CEPTRL2, Claudin 1, Claudin 7, Claudin 9, Claudin-7, Claudin1, Claudin7, Claudin9, CLD7_HUMAN, CLDN 7, CLDN-7, CLDN7, Clostridium perfringens enterotoxin receptor like 2, CPETR L2, CPETRL 2, CPETRL2, Hs. 84359

Background: Claudin 7 is a 22 kDa membrane protein, belonging to the tight junction protein family. Claudin family proteins play an important role in cell polarity, signal transduction and the pathogenesis of a variety of malignant tumors. It has been reported that compared with non neoplastic mucosal tissues, the expression of claudin 7 in laryngeal squamous cell carcinoma is down-regulated, and the expression level is related to distant metastasis, which can be used as a potential predictor of poor prognosis. Therefore, claudin 7 may be a useful immunohistochemical marker for the diagnosis, metastasis and prognosis of laryngeal cancer.

Gene Name: CLDN7 CEPTRL2 CPETRL2

Protein Name: Claudin 7

ID gène: 1366

UniProt: O95471

Pathways: Hepatitis C