CRYAA anticorps (AA 1-80)

N° du produit ABIN8120758

Cet anticorps anti-CRYAA Polyclonal Lapin (ABIN8120758) détecte spécifiquement CRYAA dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CRYAA anticorps (AA 1-80) (ABIN8120758)

Antigène: CRYAA (Crystallin, alpha A (CRYAA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRYAA est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CRYAA anticorps

Épitope: AA 1-80

Fonction: CRYAA Antibody

Specificité: CRYAA Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human protein . at AA range: 1-80

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CRYAA

Antigène: CRYAA (Crystallin, alpha A (CRYAA))

Autre désignation: CRYAA

Sujet:

Background: Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits, the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distin

Gene Name: CRYAA CRYA1 HSPB4

Protein Name: Alpha-crystallin A chain (Heat shock protein beta-4) (HspB4) [Cleaved into: Alpha-crystallin A chain, short form]

ID gène: 1409

UniProt: P02489

Pathways: M Phase