DDB2 anticorps (AA 260-340)

N° du produit ABIN8120908

Cet anticorps anti-DDB2 Polyclonal Lapin (ABIN8120908) détecte spécifiquement DDB2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour DDB2 anticorps (AA 260-340) (ABIN8120908)

Antigène: DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDB2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-DDB2 anticorps

Épitope: AA 260-340

Fonction: DDB2 Antibody

Specificité: DDB2 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human protein . at AA range: 260-340

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur DDB2

Antigène: DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

Autre désignation: DDB2

Sujet:

Background: This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],

Gene Name: DDB2

Protein Name: DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2)

ID gène: 1643

UniProt: Q92466

Pathways: Réparation de l'ADN