Desmocollin 1 anticorps (AA 749-799)

N° du produit ABIN8120970

L’anticorps anti-Desmocollin 1 Polyclonal Lapin est utilisé pour la détection de Desmocollin 1 dans des échantillons de Humain et Souris. Il a été validé pour WB.

Aperçu rapide pour Desmocollin 1 anticorps (AA 749-799) (ABIN8120970)

Antigène: Desmocollin 1 (DSC1)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmocollin 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Desmocollin 1 anticorps

Épitope: AA 749-799

Fonction: DSC1 Antibody

Specificité: This antibody detects endogenous levels of DSC1 at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human DSC1 AA range: 749-799

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Desmocollin 1

Antigène: Desmocollin 1 (DSC1)

Autre désignation: DSC1

Sujet:

Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein. [provided by RefSeq, Nov 2015],

Gene Name: DSC1 CDHF1

Protein Name: DSC1

ID gène: 1823

UniProt: Q08554