DFFA anticorps (Cleaved-Ser118)

N° du produit ABIN8121030

L’anticorps anti-DFFA Polyclonal Lapin est utilisé pour la détection de DFFA dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour DFFA anticorps (Cleaved-Ser118) (ABIN8121030)

Antigène: DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DFFA est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-DFFA anticorps

Épitope: Cleaved-Ser118

Fonction: DFF45 (Cleaved-Ser118) Antibody

Specificité: This antibody detects endogenous levels of Human DFF45 (Cleaved-Ser118, protein was cleaved amino acid sequence between117-118 )

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human DFF45 (Cleaved-Ser118)

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur DFFA

Antigène: DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))

Autre désignation: DFF45

Sujet:

Synonyms: DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit, DFF-45, Inhibitor of CAD, ICAD)

Background: function:Inhibitor of the caspase-activated DNase (DFF40).,PTM:Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 CIDE-N domain.,subunit:Heterodimer of DFFA and DFFB.,

Gene Name: DFFA DFF1 DFF45 H13

Protein Name: DFF45 (Cleaved-Ser118)

ID gène: 1676

UniProt: O00273

Pathways: Apoptose, Caspase Cascade in Apoptosis