FBXO32 anticorps (AA 217-267)

N° du produit ABIN8121360

L’anticorps anti-FBXO32 Polyclonal Lapin est utilisé pour la détection de FBXO32 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour FBXO32 anticorps (AA 217-267) (ABIN8121360)

Antigène: FBXO32 (F-Box Protein 32 (FBXO32))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO32 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FBXO32 anticorps

Épitope: AA 217-267

Fonction: FBX32 Antibody

Specificité: This antibody detects endogenous levels of FBX32 at Human/Mouse/Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human FBX32 AA range: 217-267

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur FBXO32

Antigène: FBXO32 (F-Box Protein 32 (FBXO32))

Autre désignation: FBX32

Sujet:

Synonyms: F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx)

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011],

Gene Name: FBXO32

Protein Name: FBX32

ID gène: 114907

UniProt: Q969P5