FAM111A anticorps (AA 264-314)

N° du produit ABIN8121365

Cet anticorps Lapin Polyclonal détecte spécifiquement FAM111A dans WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour FAM111A anticorps (AA 264-314) (ABIN8121365)

Antigène: FAM111A (Family with Sequence Similarity 111, Member A (FAM111A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM111A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FAM111A anticorps

Épitope: AA 264-314

Fonction: F111A Antibody

Specificité: This antibody detects endogenous levels of F111A at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human F111A AA range: 264-314

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur FAM111A

Antigène: FAM111A (Family with Sequence Similarity 111, Member A (FAM111A))

Autre désignation: F111A

Sujet:

Background: The protein encoded by this gene is cell-cycle regulated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box, that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects, consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS, also known as Gracile Bone Dysplasia), both characterized by short stature, hypoparathyroidism, bone development abnormalities, and hypocalcemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],

Gene Name: FAM111A KIAA1895

Protein Name: F111A

ID gène: 63901

UniProt: Q96PZ2